Difference between revisions of "Zinc-fingers"
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Revision as of 23:10, 8 September 2021
Zinc Finger Nucleases (ZFNs) were the first widely used programmable DNA binding protein system. ZFNs are comprised of a chain of zinc finger proteins fused to a bacterial nuclease to produce a system capable of making site-specific double stranded DNA breaks to enable gene edits. The zinc finger proteins provide site specific targeting as they each recognize a 3–4 base pair DNA sequence.
