Difference between revisions of "DNA repair pathway"

From apimba
Jump to navigation Jump to search
Line 8: Line 8:
 
==Introduction==
 
==Introduction==
 
The DNA in the genome of a cell functions as a blueprint for life. If that blueprint is damaged then the cell will no longer be able to faithfully carry out the tasks required either for continued existence or reproduction. There are many ways, both internally and externally, that DNA can get damaged, so cells have multiple pathways to repair damage, both specific damage from known mechanisms and random damage.
 
The DNA in the genome of a cell functions as a blueprint for life. If that blueprint is damaged then the cell will no longer be able to faithfully carry out the tasks required either for continued existence or reproduction. There are many ways, both internally and externally, that DNA can get damaged, so cells have multiple pathways to repair damage, both specific damage from known mechanisms and random damage.
 +
 +
Since plants can't move around (sessile) they can't avoid environmental hazards or stresses such as toxins or high-salt soils, and since they rely on energy from the sun for metabolism (autotrophic) they are constantly exposed to harmful radiation (UV) and harmful chemical byproducts of photosynthesis (reactive oxygen species - ROS).

Revision as of 20:07, 14 August 2021

A good recent review of plant DNA repair is Raina et al Frontiers in Genetics 22 June 2021 or here.

DNA Repair in plants

  1. Direct Reversal Repair
  2. Mismatch Repair
  3. Excision repair
  4. Homologous Recombination Repair
  5. Non-homologous End-Joining

Introduction

The DNA in the genome of a cell functions as a blueprint for life. If that blueprint is damaged then the cell will no longer be able to faithfully carry out the tasks required either for continued existence or reproduction. There are many ways, both internally and externally, that DNA can get damaged, so cells have multiple pathways to repair damage, both specific damage from known mechanisms and random damage.

Since plants can't move around (sessile) they can't avoid environmental hazards or stresses such as toxins or high-salt soils, and since they rely on energy from the sun for metabolism (autotrophic) they are constantly exposed to harmful radiation (UV) and harmful chemical byproducts of photosynthesis (reactive oxygen species - ROS).